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首頁(yè) > 抗體 > 一抗 > 其它 > Fibrinogen β Monoclonal Antibody
Fibrinogen β Monoclonal Antibody
商品貨號(hào)： PLA004803
適 應(yīng) 性： 人
WB ELISA
￥600元
規(guī)格：
在線咨詢
MSDS
說(shuō)明書
商品描述
  • 發(fā)貨日期： 7
  • 基因名稱： FGB
  • 蛋白名稱： Fibrinogen beta chain
  • Human_gene_id： 2244
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2244
  • Human_swiss_prot_no： P02675
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/P02675/entry
  • Mouse_swiss_prot_no： Q8K0E8
  • Mouse_swiss_link： http://www.uniprot.org/uniprot/Q8K0E8
  • 特異性： Fibrinogen β Monoclonal Antibody detects endogenous levels of Fibrinogen β protein.
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源： Monoclonal, Mouse
  • 稀釋： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
  • 純化工藝： Affinity purification
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： FGB; Fibrinogen beta chain
  • 信號(hào)通路： Complement and coagulation cascades;
  • 功能： disease:Defects in FGB are a cause of congenital afibrinogenemia [MIM:202400]. This rare autosomal recessive disorder is characterized by bleeding that varies from mild to severe and by complete absence or extremely low levels of plasma and platelet fibrinogen.,disease:Defects in FGB are a cause of thrombophilia.,domain:A long coiled coil structure formed by 3 polypeptide chains connects the central nodule to the C-terminal domains (distal nodules). The long C-terminal ends of the alpha chains fold back, contributing a fourth strand to the coiled coil structure.,function:Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation.,online information:Fibrinogen entry,online information:The Singapore human mutation and polymorphism database,PTM:Conversion of fibrinogen to fibrin is triggered by thrombin, which cleaves fibrinopeptides A and B from alpha and beta chains, and thus exposes the N-terminal polymerization sites responsible for the formation of the soft clot. The soft clot is converted into the hard clot by factor XIIIA which catalyzes the epsilon-(gamma-glutamyl)lysine cross-linking between gamma chains (stronger) and between alpha chains (weaker) of different monomers.,similarity:Contains 1 fibrinogen C-terminal domain.,subunit:Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Secreted .
  • 組織表達(dá)： Detected in blood plasma (at protein level).
  • 科研貨號(hào)： PLA004803
Fibrinogen β Monoclonal Antibody
Catalog No PLA004803
Product information
  • 發(fā)貨日期： 7
  • 基因名稱： FGB
  • 蛋白名稱： Fibrinogen beta chain
  • Human_gene_id： 2244
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2244
  • Human_swiss_prot_no： P02675
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/P02675/entry
  • Mouse_swiss_prot_no： Q8K0E8
  • Mouse_swiss_link： http://www.uniprot.org/uniprot/Q8K0E8
  • 特異性： Fibrinogen β Monoclonal Antibody detects endogenous levels of Fibrinogen β protein.
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源： Monoclonal, Mouse
  • 稀釋： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
  • 純化工藝： Affinity purification
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： FGB; Fibrinogen beta chain
  • 信號(hào)通路： Complement and coagulation cascades;
  • 功能： disease:Defects in FGB are a cause of congenital afibrinogenemia [MIM:202400]. This rare autosomal recessive disorder is characterized by bleeding that varies from mild to severe and by complete absence or extremely low levels of plasma and platelet fibrinogen.,disease:Defects in FGB are a cause of thrombophilia.,domain:A long coiled coil structure formed by 3 polypeptide chains connects the central nodule to the C-terminal domains (distal nodules). The long C-terminal ends of the alpha chains fold back, contributing a fourth strand to the coiled coil structure.,function:Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation.,online information:Fibrinogen entry,online information:The Singapore human mutation and polymorphism database,PTM:Conversion of fibrinogen to fibrin is triggered by thrombin, which cleaves fibrinopeptides A and B from alpha and beta chains, and thus exposes the N-terminal polymerization sites responsible for the formation of the soft clot. The soft clot is converted into the hard clot by factor XIIIA which catalyzes the epsilon-(gamma-glutamyl)lysine cross-linking between gamma chains (stronger) and between alpha chains (weaker) of different monomers.,similarity:Contains 1 fibrinogen C-terminal domain.,subunit:Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Secreted .
  • 組織表達(dá)： Detected in blood plasma (at protein level).
  • 科研貨號(hào)： PLA004803
    • Hunan UPT Biotechnology Co.,Ltd
    Website：www.jx3dscan.com Servive hotline :4006916686
    E-mail：service@uptbio.com
    Address：
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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