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首頁 > 抗體 > 一抗 > 其它 > GSK3β Monoclonal Antibody
GSK3β Monoclonal Antibody
商品貨號(hào)： PLA004840
適 應(yīng) 性： 人,小鼠,大鼠,猴
WB IHC IF ELISA FCM
￥600元
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MSDS
說明書
商品描述
  • 基因名稱： GSK3B
  • 蛋白名稱： Glycogen synthase kinase-3 beta
  • Human_gene_id： 2942
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2942
  • Human_swiss_prot_no： P49841
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/P49841/entry
  • Mouse_gene_id： 56637
  • Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56637
  • Mouse_swiss_prot_no： Q9WV60
  • Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9WV60
  • Rat_gene_id： 84027
  • Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84027
  • Rat_swiss_prot_no： P18266
  • Rat_swiss_link： http://www.uniprot.org/uniprot/P18266
  • 特異性： GSK3β Monoclonal Antibody detects endogenous levels of GSK3β protein.
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Monoclonal, Mouse
  • 稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. IF 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000. Not yet tested in other applications.
  • 純化工藝： Affinity purification
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B
  • 信號(hào)通路： ErbB_HER;Chemokine;Cell_Cycle_G1S;Cell_Cycle_G2M_DNA;WNT;WNT-T CELLHedgehog;Axon guidance;Focal adhesion;T_Cell_Receptor;B_Cell_Antigen;Neurotrophin;Insulin_Receptor;Melanogenesis;Alzheimer's disease;Pathways in cancer;Colorectal cancer;Endometrial cancer;Prostate cancer;Basal cell carcinoma;
  • 功能： catalytic activity:ATP + [tau protein] = ADP + [tau protein] phosphate.,enzyme regulation:Inhibited when phosphorylated by AKT1.,function:Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells, and decreases the interaction of MUC1 with CTNNB1/beta-catenin.,PTM:Phosphorylated by AKT1 and ILK1.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer (By similarity). Interacts with CABYR, MUC1, NIN and PRUNE.,tissue specificity:Expressed in testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Cytoplasm . Nucleus . Cell membrane . The phosphorylated form shows localization to cytoplasm and cell membrane (PubMed:20937854). The MEMO1-RHOA-DIAPH1 signaling pathway controls localization of the phosphorylated form to the cell membrane (PubMed:20937854). .
  • 組織表達(dá)： Expressed in testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney. Colocalizes with EIF2AK2/PKR and TAU in the Alzheimer disease (AD) brain.
  • 科研貨號(hào)： PLA004840
GSK3β Monoclonal Antibody
Catalog No PLA004840
Product information
  • 基因名稱： GSK3B
  • 蛋白名稱： Glycogen synthase kinase-3 beta
  • Human_gene_id： 2942
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2942
  • Human_swiss_prot_no： P49841
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/P49841/entry
  • Mouse_gene_id： 56637
  • Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56637
  • Mouse_swiss_prot_no： Q9WV60
  • Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9WV60
  • Rat_gene_id： 84027
  • Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84027
  • Rat_swiss_prot_no： P18266
  • Rat_swiss_link： http://www.uniprot.org/uniprot/P18266
  • 特異性： GSK3β Monoclonal Antibody detects endogenous levels of GSK3β protein.
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Monoclonal, Mouse
  • 稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. IF 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000. Not yet tested in other applications.
  • 純化工藝： Affinity purification
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B
  • 信號(hào)通路： ErbB_HER;Chemokine;Cell_Cycle_G1S;Cell_Cycle_G2M_DNA;WNT;WNT-T CELLHedgehog;Axon guidance;Focal adhesion;T_Cell_Receptor;B_Cell_Antigen;Neurotrophin;Insulin_Receptor;Melanogenesis;Alzheimer's disease;Pathways in cancer;Colorectal cancer;Endometrial cancer;Prostate cancer;Basal cell carcinoma;
  • 功能： catalytic activity:ATP + [tau protein] = ADP + [tau protein] phosphate.,enzyme regulation:Inhibited when phosphorylated by AKT1.,function:Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells, and decreases the interaction of MUC1 with CTNNB1/beta-catenin.,PTM:Phosphorylated by AKT1 and ILK1.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer (By similarity). Interacts with CABYR, MUC1, NIN and PRUNE.,tissue specificity:Expressed in testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Cytoplasm . Nucleus . Cell membrane . The phosphorylated form shows localization to cytoplasm and cell membrane (PubMed:20937854). The MEMO1-RHOA-DIAPH1 signaling pathway controls localization of the phosphorylated form to the cell membrane (PubMed:20937854). .
  • 組織表達(dá)： Expressed in testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney. Colocalizes with EIF2AK2/PKR and TAU in the Alzheimer disease (AD) brain.
  • 科研貨號(hào)： PLA004840
    • Hunan UPT Biotechnology Co.,Ltd
    Website：www.jx3dscan.com Servive hotline :4006916686
    E-mail：service@uptbio.com
    Address：
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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