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Nkx-3.1 Monoclonal Antibody
商品貨號(hào)： PLA004958
適 應(yīng) 性： 人
WB IHC IF ELISA FCM
￥600元
規(guī)格：
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MSDS
說(shuō)明書(shū)
商品描述
  • 發(fā)貨日期： 7
  • 基因名稱： NKX3-1
  • 蛋白名稱： Homeobox protein Nkx-3.1
  • Human_gene_id： 4824
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4824
  • Human_swiss_prot_no： Q99801
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/Q99801/entry
  • Mouse_swiss_prot_no： P97436
  • Mouse_swiss_link： http://www.uniprot.org/uniprot/P97436
  • 特異性： Nkx-3.1 Monoclonal Antibody detects endogenous levels of Nkx-3.1 protein.
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源： Monoclonal, Mouse
  • 稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000.. IF 1:50-200
  • 純化工藝： Affinity purification
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書(shū)： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： NKX3-1; NKX3.1; NKX3A; Homeobox protein Nkx-3.1; Homeobox protein NK-3 homolog A
  • 信號(hào)通路： Pathways in cancer;Prostate cancer;
  • 功能： alternative products:Additional isoforms seem to exist,disease:NKX3-1 has been thought to be one of the target gene of the 8p21 loss of heterozygosity, common in prostate cancer, but neither disruption of the coding region of the gene, nor mutations have been found in prostate cancer.,function:Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Could play an important role in regulating proliferation of glandular epithelium and in the formation of ducts in prostate.,induction:By androgens and, in the LNCAP cell line, by estrogens. Androgenic control may be lost in prostate cancer cells during tumor progression from an androgen-dependent to an androgen-independent phase.,similarity:Belongs to the NK-3 homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,subunit:Interacts with serum response factor (SRF) (By similarity). Interacts with SPDEF. Interacts with WDR77.,tissue specificity:Highly expressed in the prostate and, at a lower level, in the testis.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Nucleus .
  • 組織表達(dá)： Highly expressed in the prostate and, at a lower level, in the testis.
  • 科研貨號(hào)： PLA004958
Nkx-3.1 Monoclonal Antibody
Catalog No PLA004958
Product information
  • 發(fā)貨日期： 7
  • 基因名稱： NKX3-1
  • 蛋白名稱： Homeobox protein Nkx-3.1
  • Human_gene_id： 4824
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4824
  • Human_swiss_prot_no： Q99801
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/Q99801/entry
  • Mouse_swiss_prot_no： P97436
  • Mouse_swiss_link： http://www.uniprot.org/uniprot/P97436
  • 特異性： Nkx-3.1 Monoclonal Antibody detects endogenous levels of Nkx-3.1 protein.
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源： Monoclonal, Mouse
  • 稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000.. IF 1:50-200
  • 純化工藝： Affinity purification
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書(shū)： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： NKX3-1; NKX3.1; NKX3A; Homeobox protein Nkx-3.1; Homeobox protein NK-3 homolog A
  • 信號(hào)通路： Pathways in cancer;Prostate cancer;
  • 功能： alternative products:Additional isoforms seem to exist,disease:NKX3-1 has been thought to be one of the target gene of the 8p21 loss of heterozygosity, common in prostate cancer, but neither disruption of the coding region of the gene, nor mutations have been found in prostate cancer.,function:Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Could play an important role in regulating proliferation of glandular epithelium and in the formation of ducts in prostate.,induction:By androgens and, in the LNCAP cell line, by estrogens. Androgenic control may be lost in prostate cancer cells during tumor progression from an androgen-dependent to an androgen-independent phase.,similarity:Belongs to the NK-3 homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,subunit:Interacts with serum response factor (SRF) (By similarity). Interacts with SPDEF. Interacts with WDR77.,tissue specificity:Highly expressed in the prostate and, at a lower level, in the testis.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Nucleus .
  • 組織表達(dá)： Highly expressed in the prostate and, at a lower level, in the testis.
  • 科研貨號(hào)： PLA004958
    • Hunan UPT Biotechnology Co.,Ltd
    Website：www.jx3dscan.com Servive hotline :4006916686
    E-mail：service@uptbio.com
    Address：
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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4006916686

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