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首頁 > 抗體 > 一抗 > 其它 > OCT1 Monoclonal Antibody
OCT1 Monoclonal Antibody
商品貨號： PLA004963
適 應(yīng) 性： 人
WB ELISA FCM
￥600元
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MSDS
說明書
商品描述
  • 發(fā)貨日期： 7
  • 基因名稱： SLC22A1
  • 蛋白名稱： Solute carrier family 22 member 1
  • Human_gene_id： 6580
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6580
  • Human_swiss_prot_no： O15245
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/O15245/entry
  • Mouse_swiss_prot_no： O08966
  • Mouse_swiss_link： http://www.uniprot.org/uniprot/O08966
  • 特異性： OCT1 Monoclonal Antibody detects endogenous levels of 41183 protein.
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Monoclonal, Mouse
  • 稀釋： WB 1:500 - 1:2000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000. Not yet tested in other applications.
  • 純化工藝： Affinity purification
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： SLC22A1; OCT1; Solute carrier family 22 member 1; Organic cation transporter 1; hOCT1
  • 功能： caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1-methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1-methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N-methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA receptor antagonists, atropine, prazosin, cimetidine, TEA and NMN, guanidine, cimetidine, choline, procainamide, quinine, tetrabutylammonium, and tetrapentylammonium. Translocates organic cations in an electrogenic and pH-independent manner. Translocates organic cations across the plasma membrane in both directions. Transports the polyamines spermine and spermidine. Transports pramipexole across the basolateral membrane of the proximal tubular epithelial cells. The choline transport is activated by MMTS. Regulated by various intracellular signaling pathways including inhibition by protein kinase A activation, and endogenously activation by the calmodulin complex, the calmodulin-dependent kinase II and LCK tyrosine kinase.,induction:In the liver activated by HNF4A and suppressed by bile acids via NR0B2. Increased by cholesterol treatment in hepatocyte cells.,PTM:Phosphorylated.,similarity:Belongs to the major facilitator superfamily. Organic cation transporter family.,tissue specificity:Widely expressed with high level in liver. Isoform 1 and isoform 2 are expressed in liver. Isoform 1, isoform 2, isoform 3 and isoform 4 are expressed in glial cell lines.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Basolateral cell membrane ; Multi-pass membrane protein .
  • 組織表達(dá)： Widely expressed with high level in liver. Isoform 1 and isoform 2 are expressed in liver. Isoform 1, isoform 2, isoform 3 and isoform 4 are expressed in glial cell lines.
  • 科研貨號： PLA004963
OCT1 Monoclonal Antibody
Catalog No PLA004963
Product information
  • 發(fā)貨日期： 7
  • 基因名稱： SLC22A1
  • 蛋白名稱： Solute carrier family 22 member 1
  • Human_gene_id： 6580
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6580
  • Human_swiss_prot_no： O15245
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/O15245/entry
  • Mouse_swiss_prot_no： O08966
  • Mouse_swiss_link： http://www.uniprot.org/uniprot/O08966
  • 特異性： OCT1 Monoclonal Antibody detects endogenous levels of 41183 protein.
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Monoclonal, Mouse
  • 稀釋： WB 1:500 - 1:2000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000. Not yet tested in other applications.
  • 純化工藝： Affinity purification
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： SLC22A1; OCT1; Solute carrier family 22 member 1; Organic cation transporter 1; hOCT1
  • 功能： caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1-methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1-methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N-methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA receptor antagonists, atropine, prazosin, cimetidine, TEA and NMN, guanidine, cimetidine, choline, procainamide, quinine, tetrabutylammonium, and tetrapentylammonium. Translocates organic cations in an electrogenic and pH-independent manner. Translocates organic cations across the plasma membrane in both directions. Transports the polyamines spermine and spermidine. Transports pramipexole across the basolateral membrane of the proximal tubular epithelial cells. The choline transport is activated by MMTS. Regulated by various intracellular signaling pathways including inhibition by protein kinase A activation, and endogenously activation by the calmodulin complex, the calmodulin-dependent kinase II and LCK tyrosine kinase.,induction:In the liver activated by HNF4A and suppressed by bile acids via NR0B2. Increased by cholesterol treatment in hepatocyte cells.,PTM:Phosphorylated.,similarity:Belongs to the major facilitator superfamily. Organic cation transporter family.,tissue specificity:Widely expressed with high level in liver. Isoform 1 and isoform 2 are expressed in liver. Isoform 1, isoform 2, isoform 3 and isoform 4 are expressed in glial cell lines.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Basolateral cell membrane ; Multi-pass membrane protein .
  • 組織表達(dá)： Widely expressed with high level in liver. Isoform 1 and isoform 2 are expressed in liver. Isoform 1, isoform 2, isoform 3 and isoform 4 are expressed in glial cell lines.
  • 科研貨號： PLA004963
    • Hunan UPT Biotechnology Co.,Ltd
    Website：www.jx3dscan.com Servive hotline :4006916686
    E-mail：service@uptbio.com
    Address：
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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