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首頁(yè) > 抗體 > 一抗 > 其它 > Oct-3/4 Monoclonal Antibody
Oct-3/4 Monoclonal Antibody
商品貨號(hào): PLA004964
適 應(yīng) 性:
WB IF ELISA FCM
¥600元
規(guī)格:
在線咨詢
MSDS
說(shuō)明書(shū)
商品描述
  • 發(fā)貨日期: 7
  • 基因名稱: POU5F1
  • 蛋白名稱: POU domain class 5 transcription factor 1
  • Human_gene_id: 5460
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5460
  • Human_swiss_prot_no: Q01860
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q01860/entry
  • Mouse_swiss_prot_no: P20263
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P20263
  • 特異性: Oct-3/4 Monoclonal Antibody detects endogenous levels of Oct-3/4 protein.
  • 組成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源: Monoclonal, Mouse
  • 稀釋: WB 1:500 - 1:2000. IF 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000. Not yet tested in other applications.
  • 純化工藝: Affinity purification
  • 儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書(shū): 1
  • Msds: MSDS_Antibody.pdf
  • 其他名稱: POU5F1; OCT3; OCT4; OTF3; POU domain; class 5, transcription factor 1; Octamer-binding protein 3; Oct-3; Octamer-binding protein 4; Oct-4; Octamer-binding transcription factor 3; OTF-3
  • 功能: function:Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.,miscellaneous:Several pseudogenes of POU5F1 have been described on chromosomes 1, 3, 8, 10 and 12. 2 of them, localized in chromosomes 8 and 10, are transcribed in cancer tissues but not in normal ones and may be involved in the regulation of POU5F1 gene activity in carcinogenesis.,online information:Oct-4 entry,PTM:Sumoylation enhances the protein stability, DNA binding and transactivation activity. Sumoylation is required for enhanced YES1 expression.,similarity:Belongs to the POU transcription factor family. Class-5 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,subcellular location:Expressed in a diffuse and slightly punctuate pattern.,subunit:Interacts with UBE2I.,tissue specificity:Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.,
  • 相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位: Cytoplasm. Nucleus. Expressed in a diffuse and slightly punctuate pattern. Colocalizes with MAPK8 and MAPK9 in the nucleus. .
  • 組織表達(dá): Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.
  • tag: hot
  • 科研貨號(hào): PLA004964
Oct-3/4 Monoclonal Antibody
Catalog No PLA004964
Product information
  • 發(fā)貨日期: 7
  • 基因名稱: POU5F1
  • 蛋白名稱: POU domain class 5 transcription factor 1
  • Human_gene_id: 5460
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5460
  • Human_swiss_prot_no: Q01860
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q01860/entry
  • Mouse_swiss_prot_no: P20263
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P20263
  • 特異性: Oct-3/4 Monoclonal Antibody detects endogenous levels of Oct-3/4 protein.
  • 組成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源: Monoclonal, Mouse
  • 稀釋: WB 1:500 - 1:2000. IF 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000. Not yet tested in other applications.
  • 純化工藝: Affinity purification
  • 儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書(shū): 1
  • Msds: MSDS_Antibody.pdf
  • 其他名稱: POU5F1; OCT3; OCT4; OTF3; POU domain; class 5, transcription factor 1; Octamer-binding protein 3; Oct-3; Octamer-binding protein 4; Oct-4; Octamer-binding transcription factor 3; OTF-3
  • 功能: function:Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.,miscellaneous:Several pseudogenes of POU5F1 have been described on chromosomes 1, 3, 8, 10 and 12. 2 of them, localized in chromosomes 8 and 10, are transcribed in cancer tissues but not in normal ones and may be involved in the regulation of POU5F1 gene activity in carcinogenesis.,online information:Oct-4 entry,PTM:Sumoylation enhances the protein stability, DNA binding and transactivation activity. Sumoylation is required for enhanced YES1 expression.,similarity:Belongs to the POU transcription factor family. Class-5 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,subcellular location:Expressed in a diffuse and slightly punctuate pattern.,subunit:Interacts with UBE2I.,tissue specificity:Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.,
  • 相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位: Cytoplasm. Nucleus. Expressed in a diffuse and slightly punctuate pattern. Colocalizes with MAPK8 and MAPK9 in the nucleus. .
  • 組織表達(dá): Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.
  • tag: hot
  • 科研貨號(hào): PLA004964
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.jx3dscan.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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