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首頁 > 抗體 > 一抗 > 其它 > Rtn-3 Monoclonal Antibody
Rtn-3 Monoclonal Antibody
商品貨號： PLA005025
適 應(yīng) 性： 人
IF ELISA
￥600元
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MSDS
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商品描述
  • 發(fā)貨日期： 7
  • 基因名稱： RTN3
  • 蛋白名稱： Reticulon-3
  • Human_gene_id： 10313
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10313
  • Human_swiss_prot_no： O95197
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/O95197/entry
  • Mouse_swiss_prot_no： Q9ES97
  • Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9ES97
  • 特異性： Rtn-3 Monoclonal Antibody detects endogenous levels of Rtn-3 protein.
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Monoclonal, Mouse
  • 稀釋： IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
  • 純化工藝： Affinity purification
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： RTN3; ASYIP; NSPL2; Reticulon-3; Neuroendocrine-specific protein-like 2; NSP-like protein 2; Neuroendocrine-specific protein-like II; NSP-like protein II; NSPLII
  • 信號通路： Regulation of Microtubule Dynamics; Regulation of Actin Dynamics; SAPK_JNK; Stem cell pathway; Adherens_Junction
  • 功能： function:May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis.,induction:By endoplasmic reticulum stress (at protein level).,miscellaneous:The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.,similarity:Contains 1 reticulon domain.,subunit:Homodimer. Interacts with RTN4. Isoform 3 interacts with BACE1, BACE2, BCL2 and FADD. Interacts with Coxsackievirus A16, enterovirus 71 and poliovirus P2C proteins.,tissue specificity:Isoform 3 is widely expressed, with highest levels in brain, where it is enriched in neuronal cell bodies from gray matter (at protein level). Three times more abundant in macula than in peripheral retina. Isoform 1 is expressed at high levels in brain and at low levels in skeletal muscle. Isoform 2 is only found in melanoma.,
  • 相關(guān)產(chǎn)品： YM0568,YM0567,RS0001,RS0002,YM3028,YM3029
  • 細胞定位： Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein .
  • 組織表達： Isoform 3 is widely expressed, with highest levels in brain, where it is enriched in neuronal cell bodies from gray matter (at protein level). Three times more abundant in macula than in peripheral retina. Isoform 1 is expressed at high levels in brain and at low levels in skeletal muscle. Isoform 2 is only found in melanoma.
  • 科研貨號： PLA005025
Rtn-3 Monoclonal Antibody
Catalog No PLA005025
Product information
  • 發(fā)貨日期： 7
  • 基因名稱： RTN3
  • 蛋白名稱： Reticulon-3
  • Human_gene_id： 10313
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10313
  • Human_swiss_prot_no： O95197
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/O95197/entry
  • Mouse_swiss_prot_no： Q9ES97
  • Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9ES97
  • 特異性： Rtn-3 Monoclonal Antibody detects endogenous levels of Rtn-3 protein.
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Monoclonal, Mouse
  • 稀釋： IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
  • 純化工藝： Affinity purification
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： RTN3; ASYIP; NSPL2; Reticulon-3; Neuroendocrine-specific protein-like 2; NSP-like protein 2; Neuroendocrine-specific protein-like II; NSP-like protein II; NSPLII
  • 信號通路： Regulation of Microtubule Dynamics; Regulation of Actin Dynamics; SAPK_JNK; Stem cell pathway; Adherens_Junction
  • 功能： function:May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis.,induction:By endoplasmic reticulum stress (at protein level).,miscellaneous:The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.,similarity:Contains 1 reticulon domain.,subunit:Homodimer. Interacts with RTN4. Isoform 3 interacts with BACE1, BACE2, BCL2 and FADD. Interacts with Coxsackievirus A16, enterovirus 71 and poliovirus P2C proteins.,tissue specificity:Isoform 3 is widely expressed, with highest levels in brain, where it is enriched in neuronal cell bodies from gray matter (at protein level). Three times more abundant in macula than in peripheral retina. Isoform 1 is expressed at high levels in brain and at low levels in skeletal muscle. Isoform 2 is only found in melanoma.,
  • 相關(guān)產(chǎn)品： YM0568,YM0567,RS0001,RS0002,YM3028,YM3029
  • 細胞定位： Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein .
  • 組織表達： Isoform 3 is widely expressed, with highest levels in brain, where it is enriched in neuronal cell bodies from gray matter (at protein level). Three times more abundant in macula than in peripheral retina. Isoform 1 is expressed at high levels in brain and at low levels in skeletal muscle. Isoform 2 is only found in melanoma.
  • 科研貨號： PLA005025
    • Hunan UPT Biotechnology Co.,Ltd
    Website：www.jx3dscan.com Servive hotline :4006916686
    E-mail：service@uptbio.com
    Address：
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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