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SOX-2 Monoclonal Antibody
商品貨號(hào)： PLA005044
適 應(yīng) 性： 人
WB IHC IF ELISA
￥600元
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MSDS
說明書
商品描述
  • 發(fā)貨日期： 7
  • 基因名稱： SOX2
  • 蛋白名稱： Transcription factor SOX-2
  • Human_gene_id： 6657
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6657
  • Human_swiss_prot_no： P48431
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/P48431/entry
  • Mouse_swiss_prot_no： P48432
  • Mouse_swiss_link： http://www.uniprot.org/uniprot/P48432
  • 特異性： SOX-2 Monoclonal Antibody detects endogenous levels of SOX-2 protein.
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Monoclonal, Mouse
  • 稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
  • 純化工藝： Affinity purification
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： SOX2; Transcription factor SOX-2
  • 功能： disease:Defects in SOX2 are the cause of microphthalmia syndromic type 3 (MCOPS3) [MIM:206900]. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities. MCOPS3 is characterized by the rare association of malformations including uni- or bilateral anophthalmia or microphthalmia, and esophageal atresia with trachoesophageal fistula.,function:Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.,online information:Sox2 entry,PTM:Sumoylation inhibits binding on DNA and negatively regulates the FGF4 transactivation.,similarity:Contains 1 HMG box DNA-binding domain.,
  • 相關(guān)產(chǎn)品： YM1221,YM1099,YM0594,YM0593
  • 細(xì)胞定位： Nucleus speckle . Cytoplasm . Nucleus . Acetylation contributes to its nuclear localization and deacetylation by HDAC3 induces a cytoplasmic delocalization (By similarity). Colocalizes in the nucleus with ZNF208 isoform KRAB-O and tyrosine hydroxylase (TH) (By similarity). Colocalizes with SOX6 in speckles. Colocalizes with CAML in the nucleus (By similarity). Nuclear import is facilitated by XPO4, a protein that usually acts as a nuclear export signal receptor (By similarity). .
  • 組織表達(dá)： Fetal brain,Lung,Retina,
  • tag： hot
  • 科研貨號(hào)： PLA005044
SOX-2 Monoclonal Antibody
Catalog No PLA005044
Product information
  • 發(fā)貨日期： 7
  • 基因名稱： SOX2
  • 蛋白名稱： Transcription factor SOX-2
  • Human_gene_id： 6657
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6657
  • Human_swiss_prot_no： P48431
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/P48431/entry
  • Mouse_swiss_prot_no： P48432
  • Mouse_swiss_link： http://www.uniprot.org/uniprot/P48432
  • 特異性： SOX-2 Monoclonal Antibody detects endogenous levels of SOX-2 protein.
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Monoclonal, Mouse
  • 稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
  • 純化工藝： Affinity purification
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： SOX2; Transcription factor SOX-2
  • 功能： disease:Defects in SOX2 are the cause of microphthalmia syndromic type 3 (MCOPS3) [MIM:206900]. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities. MCOPS3 is characterized by the rare association of malformations including uni- or bilateral anophthalmia or microphthalmia, and esophageal atresia with trachoesophageal fistula.,function:Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.,online information:Sox2 entry,PTM:Sumoylation inhibits binding on DNA and negatively regulates the FGF4 transactivation.,similarity:Contains 1 HMG box DNA-binding domain.,
  • 相關(guān)產(chǎn)品： YM1221,YM1099,YM0594,YM0593
  • 細(xì)胞定位： Nucleus speckle . Cytoplasm . Nucleus . Acetylation contributes to its nuclear localization and deacetylation by HDAC3 induces a cytoplasmic delocalization (By similarity). Colocalizes in the nucleus with ZNF208 isoform KRAB-O and tyrosine hydroxylase (TH) (By similarity). Colocalizes with SOX6 in speckles. Colocalizes with CAML in the nucleus (By similarity). Nuclear import is facilitated by XPO4, a protein that usually acts as a nuclear export signal receptor (By similarity). .
  • 組織表達(dá)： Fetal brain,Lung,Retina,
  • tag： hot
  • 科研貨號(hào)： PLA005044
    • Hunan UPT Biotechnology Co.,Ltd
    Website：www.jx3dscan.com Servive hotline :4006916686
    E-mail：service@uptbio.com
    Address：
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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