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首頁(yè) > 抗體 > 兔單抗 > Importin 9 (PT1134R) PT® Rabbit mAb
Importin 9 (PT1134R) PT® Rabbit mAb
商品貨號(hào)： PRM8784
適 應(yīng) 性： 人,小鼠
WB IHC IP FC
￥800元
規(guī)格：
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商品描述
  • 發(fā)貨日期： 現(xiàn)貨
  • 靶點(diǎn)-Target： Importin 9
  • 反應(yīng)性-Reactivity： 人,小鼠
  • 應(yīng)用-Applications： WB,IHC,ICC/IF,FC,IP
  • MW(Calculated)： 115kDa
  • MW(Observed)： 115kDa
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 偶聯(lián)-Conjugate： Unmodified
  • 推薦稀釋比： IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;IP 1:50-1:200;FC 1:100-1:500;
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆號(hào)： PT1134R
  • 特異性： Endogenous
  • 基因名稱： IPO9 IMP9 KIAA1192 RANBP9 HSPC273
  • 蛋白名稱： Importin-9 (Imp9) (Ran-binding protein 9) (RanBP9)
  • Organism-1： Human
  • 基因ID-1： 55705
  • SwissProt-1： Q96P70
  • Organism-2： Mouse
  • SwissProt-2： Q91YE6
  • 背景： function:Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of H2B histone (By similarity), RPS7 and RPL18A. Prevents the cytoplasmic aggregation of RPS7 and RPL18A by shielding exposed basic domains. May also import H2A, H3, H4 histones (By similarity), RPL4 and RPL6.,similarity:Belongs to the importin beta family.,similarity:Contains 1 importin N-terminal domain.,subunit:Binds with high affinity to RPS7 and RPL18A. The binding is coupled to RanGTP cycles. May bind H2A, H3, H4 histones (By similarity), RPL4 and RPL6 with low affinity. Interacts with PPP2R1A and PPP2R1B.,
  • 細(xì)胞定位： Cytoplasm . Nucleus .
Importin 9 (PT1134R) PT® Rabbit mAb
Catalog No PRM8784
Product information
  • 發(fā)貨日期： 現(xiàn)貨
  • 靶點(diǎn)-Target： Importin 9
  • 反應(yīng)性-Reactivity： 人,小鼠
  • 應(yīng)用-Applications： WB,IHC,ICC/IF,FC,IP
  • MW(Calculated)： 115kDa
  • MW(Observed)： 115kDa
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 偶聯(lián)-Conjugate： Unmodified
  • 推薦稀釋比： IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;IP 1:50-1:200;FC 1:100-1:500;
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆號(hào)： PT1134R
  • 特異性： Endogenous
  • 基因名稱： IPO9 IMP9 KIAA1192 RANBP9 HSPC273
  • 蛋白名稱： Importin-9 (Imp9) (Ran-binding protein 9) (RanBP9)
  • Organism-1： Human
  • 基因ID-1： 55705
  • SwissProt-1： Q96P70
  • Organism-2： Mouse
  • SwissProt-2： Q91YE6
  • 背景： function:Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of H2B histone (By similarity), RPS7 and RPL18A. Prevents the cytoplasmic aggregation of RPS7 and RPL18A by shielding exposed basic domains. May also import H2A, H3, H4 histones (By similarity), RPL4 and RPL6.,similarity:Belongs to the importin beta family.,similarity:Contains 1 importin N-terminal domain.,subunit:Binds with high affinity to RPS7 and RPL18A. The binding is coupled to RanGTP cycles. May bind H2A, H3, H4 histones (By similarity), RPL4 and RPL6 with low affinity. Interacts with PPP2R1A and PPP2R1B.,
  • 細(xì)胞定位： Cytoplasm . Nucleus .
    • Hunan UPT Biotechnology Co.,Ltd
    Website：www.jx3dscan.com Servive hotline :4006916686
    E-mail：service@uptbio.com
    Address：
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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