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首頁 > 抗體 > 兔單抗 > SREBP-1 Rabbit mAb
SREBP-1 Rabbit mAb
商品貨號: PRM8794
適 應(yīng) 性: 人,小鼠,大鼠
WB IHC IF ELISA IP
¥7000元
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商品描述
  • 發(fā)貨日期: 現(xiàn)貨
  • 靶點(diǎn)-Target: SREBP-1
  • 反應(yīng)性-Reactivity: 人,小鼠,大鼠
  • 應(yīng)用-Applications: WB,IHC,IF,IP,ELISA
  • MW(Calculated): 122kD
  • MW(Observed): 125kD
  • 宿主物種-Host Species: Rabbit
  • 同種型-Isotype: IgG,Kappa
  • 偶聯(lián)-Conjugate: Unmodified
  • 推薦稀釋比: IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝: Protein A
  • 儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性: Monoclonal
  • 克隆號: PT0883R
  • 特異性: Endogenous
  • 基因名稱: SREBF1 BHLHD1 SREBP1
  • 蛋白名稱: SREBP-1
  • 別名: Sterol regulatory element-binding protein 1;SREBP-1;Class D basic helix-loop-helix protein 1;bHLHd1;Sterol regulatory element-binding transcription factor 1;[Cleaved into: Processed sterol regulatory element-binding protein 1]
  • Organism-1: Human
  • 基因ID-1: 6720
  • SwissProt-1: P36956
  • Organism-2: Mouse
  • 基因ID-2: 20787
  • SwissProt-2: Q9WTN3
  • Organism-3: Rat
  • 基因ID-3: 78968
  • SwissProt-3: P56720
  • 背景: This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Mar 2016],
  • 細(xì)胞定位: [Sterol regulatory element-binding protein 1]: Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein . Cytoplasmic vesicle, COPII-coated vesicle membrane ; Multi-pass membrane protein . At high sterol concentrations, the SCAP-SREBP is retained in the endoplasmic reticulum. Low sterol concentrations promote recruitment into COPII-coated vesicles and transport of the SCAP-SREBP to the Golgi, where it is processed. .; [Processed sterol regulatory element-binding protein 1]: Nucleus .; [Isoform SREBP-1aDelta]: Nucleus .; [Isoform SREBP-1cDelta]: Nucleus .
SREBP-1 Rabbit mAb
Catalog No PRM8794
Product information
  • 發(fā)貨日期: 現(xiàn)貨
  • 靶點(diǎn)-Target: SREBP-1
  • 反應(yīng)性-Reactivity: 人,小鼠,大鼠
  • 應(yīng)用-Applications: WB,IHC,IF,IP,ELISA
  • MW(Calculated): 122kD
  • MW(Observed): 125kD
  • 宿主物種-Host Species: Rabbit
  • 同種型-Isotype: IgG,Kappa
  • 偶聯(lián)-Conjugate: Unmodified
  • 推薦稀釋比: IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝: Protein A
  • 儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性: Monoclonal
  • 克隆號: PT0883R
  • 特異性: Endogenous
  • 基因名稱: SREBF1 BHLHD1 SREBP1
  • 蛋白名稱: SREBP-1
  • 別名: Sterol regulatory element-binding protein 1;SREBP-1;Class D basic helix-loop-helix protein 1;bHLHd1;Sterol regulatory element-binding transcription factor 1;[Cleaved into: Processed sterol regulatory element-binding protein 1]
  • Organism-1: Human
  • 基因ID-1: 6720
  • SwissProt-1: P36956
  • Organism-2: Mouse
  • 基因ID-2: 20787
  • SwissProt-2: Q9WTN3
  • Organism-3: Rat
  • 基因ID-3: 78968
  • SwissProt-3: P56720
  • 背景: This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Mar 2016],
  • 細(xì)胞定位: [Sterol regulatory element-binding protein 1]: Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein . Cytoplasmic vesicle, COPII-coated vesicle membrane ; Multi-pass membrane protein . At high sterol concentrations, the SCAP-SREBP is retained in the endoplasmic reticulum. Low sterol concentrations promote recruitment into COPII-coated vesicles and transport of the SCAP-SREBP to the Golgi, where it is processed. .; [Processed sterol regulatory element-binding protein 1]: Nucleus .; [Isoform SREBP-1aDelta]: Nucleus .; [Isoform SREBP-1cDelta]: Nucleus .
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.jx3dscan.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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